Lighthouse Guild’s Research Team is actively publishing evidence-based findings on their collaborative work with academic and industry leaders. Chief Research Officer and Principal Investigator, Dr. William H. Seiple, has coauthored over 200 articles during his remarkable career. This section includes publications from the last five years in reverse chronological order. 

Performance on Activities of Daily Living and User Experience When Using Artificial Intelligence by Individuals with Vision Impairment.  Seiple W, van der Aa HPA, Garcia-Piña, F, Greco I, Roberts R, van Nispen R; Trans. Vis. Sci. Tech. 2025;14(1):3. doi: https://doi.org/10.1167/tvst.14.1.3

Performance on clinical outcomes, activities of daily living and user experience on head-mounted displays for people with vision impairment. Aa HPA, Garcia-Piña, F, Greco I, Roberts R, van Nispen R, Seiple W. Ophthalmic Physiol Opt. 2024;44:840–853. doi:10.1111/opo.13329

Association of Psychosocial Factors with Activation Among Patients with Glaucoma.  Morse, Alan R; Hark, Lisa A; Gorroochurn, Prakash; Rojas, Rebecca; Seiple, William H; Shukla, Aakriti G; Wang, Yujia; Maruri, Stefania C; Henriquez, Desiree R; Harizman, Noga; Wang, Qing; Liebmann, Jeffrey M; Cioffi, George A. Ophthalmology, Glaucoma. 2024;(4):410-417. doi:10.1016/j.ogla.2024.01.008 

Foveal drusen increase fixation instability: fixational eye movements as biomarkers for pre-symptomatic AMD. Murari J, GautierJ, Daout J, Krafft L, Senée P, Mecê P, Seiple W, Grieve K, Sheynikhovich D, Meimon S, Paques M, Arleo A. 2024.  doi:10.1167/iovs.65.8.13

Virtual reality as a means to explore assistive technologies for the visually impaired. Ricci FS, Boldini, Ma X, Beheshi, M. Geruschat DR, Seiple WH, Rizzo JR, Porfiri M. PLOS Digital Health, 2023. doi:10.1371/journal.pdig.0000275

A Smart Service System for Spatial Intelligence and Onboard Navigation for Individuals with Visual Impairment (VIS4ION Thailand): study protocol of a randomized controlled trial of visually impaired students at the Ratchasuda College, Thailand. Beheshti M, Naeimi T, Hudson TE, Feng C, Mongkolwat P, Riewpaiboon W, Seiple W, Vedanthan R, Rizzo JR. Trials. 2023:24(1). doi:10.1186/s13063-023-07173-8

Wearables for Persons with Blindness and Low Vision: Form Factor Matters. Han YH, Beheshti M, Jones B, Hudson T, Seiple WH, Rizzo JR. Assistive technology. 2023 1-4. doi:10.1080/10400435.2023.2205490

The global crisis of visual impairment: an emerging global health priority requiring urgent action. Rizzo JR, Beheshti M, Hudson TE, Seiple W, …. Disability & rehabilitation. Assistive technology 18, 240-245, 2023. doi:10.1080/17483107.2020.1854876

The BLV App Arcade: a new curated repository and evaluation rubric for mobile applications supporting blindness and low vision. Liu BM, Beheshti M, Naeimi T, Zhu Z, Vedanthan R, Seiple W, et al. Disability and Rehabilitation: Assistive TechnologIy 2023: 1-10. doi:10.1080/17483107.2023.2187094

An AI-Enabled Storefront Accessibility Annotation Platform. Wang W, Liu J, Hao Tang H, Zhu Z, Seiple W. Journal on Technology and Persons with Disabilities: Journal on Technology and Persons with Disabilities, 2023, Volume 11.
http://hdl.handle.net/10211.3/225166 

Digital Technologies in Orientation and Mobility Instruction for People Who Are Blind or Have Low Vision. Dove G, Fernando A, Hertz K, Kim J, Rizzo JR, Seiple W, Nov O. Proceedings of the ACM on Human-Computer Interaction, 6, 1–25. 2022. doi:https://doi.org/10.1145/3555622

Crowdsourcing Annotating Storefront Accessibility Data Using Crowdsourcing. Liu J, Tang H, Seiple W, Zhu Z. The Journal on Technology and Persons with Disabilities, 15, 2022. http://hdl.handle.net/10211.3/223472

Network aware 5G edge computing for object detection: Augmenting wearables to “see” more, farther and faster. Yuan Z, Azzino T, Hao Y, Seiple W. IEEE Access: practical innovations, open solutions, 2022. doi:10.1109/ACCESS.2022.3157876

Activation in individuals with vision loss. Morse AR, Seiple W. Journal of Health Psychology 26:2603–2612, 2021. doi:10.1177/1359105320922303

ASSIST: Assistive Sensor Solutions for Independent and Safe Travel of Blind and Visually Impaired People. Zhu Z, Nair V, Olmschenk G, Seiple W (2021). IJCAI Workshop on AI for Social Good, 2021. https://crcs.seas.harvard.edu/sites/g/files/omnuum6171/files/crcs/files/ai4sg-21_paper_2.pdf 

Active crowd analysis for pandemic risk mitigation for blind or visually impaired persons. Shrestha S, Lu D, Tian H, Cao Q, Liu J, Rizzo JR, Seiple WH, Porfiri M, Fang Y., Eighth International Workshop on Assistive Computer Vision and Robotics, Glasgow, UK, 2021. doi:https://doi.org/10.1007/978-3-030-66823-5_25

Potential transferable skills from eccentric viewing training. Murphy C, H Boxerman H, Seiple W, Clark RA, Li KH, Marinier JA. Visibility 15 (2), 1-11, 2021. https://research.usc.edu.au/esploro/outputs/99534605802621 

Visual search performance across adulthood and in individuals with AMD. Agathos C, Tremolada A, Benziane B, Lagrené K, Seiple WH, Arleo A. Investigative Ophthalmology and Visual Science, 62(8):518, 2021. http://iovs.arvojournals.org/article.aspx?articleid=2774591 

Reduction in mammography screening for breast cancer among visually impaired women. Wu AM, Morse AR, Seiple W, Talwar N, Hansen SO, Lee PP, Stein JD. (2020). Ophthalmology. 2021:128(2):317-323. doi:10.1016/j.ophtha.2020.07.029

Decreasing avoidable vision loss: identifying antecedents of adherence. Morse AR, Seiple WH. Clinical Ophthalmology, 14:3735-3739, 2020. doi:10.2147/OPTH.S278627

Smart and accessible transportation hub for assistive navigation and facility management. Zhu Z, Gong J, Feeley C, Vo H, Tang H, Ruci A, Seiple WH, Wu Z, Harvard CRCS Workshop on AI for Social Good, 2020. https://crcs.seas.harvard.edu/sites/g/files/omnuum6171/files/crcs/files/ai4sg_2020_paper_4.pdf 

Smartphone usage in a general low vision clinic population. Maeng M, Grant P, Szlyk JP, Seiple WH. Investigative Ophthalmology and Visual Science, 61(7):931, 2020.  http://iovs.arvojournals.org/article.aspx?articleid=2766797

The Relationship Between Cognitive Status and Known Single Nucleotide Polymorphisms in Age-related Macular Degeneration. Murphy CE, Johnson AP, Koenekoop RK, Seiple W, Overbury O. Frontiers in Aging Neuroscience, 16,12:586691, 2020. doi:10.3389/fnagi.2020.586691

Evaluating the Usability and Performance of an Indoor Navigation Assistant for the Blind and Visually Impaired. Naira V, Olmschenk G, Seiple W, Zhu A. Assistive Technology, The Official Journal of RESNA,Sep 02, 1-11, 2020. doi:10.1080/10400435.2020.1809553

Join our Mission

Lighthouse Guild is dedicated to providing exceptional services that inspire people who are visually impaired to attain their goals.

Join our Mission